Paula Annukka Nousiainen

Oxidative crosslinking for the development of barrier coatings utilizing lignin-containing cellulose nanofibrils and lignin nanoparticles

Sahar Babaeipour, Paula Nousiainen, Elijah Mark Garcia, Pezhman Mohammadi, Maija Vuoriluoto, Erfan Kimiaei, Hanna Koivula, Monika Österberg 2025 Food Packaging and Shelf Life

Cell Wall Polymer Degradation during Rhodonia placenta Brown Rot Decay of Thermally Modified and Unmodified Wood

Tiina Belt, Muhammad Awais, Paula Nousiainen, Lauri Rautkari, Mikko Mäkelä 2025 ACS Sustainable Chemistry & Engineering

Supramolecular Architectures Based on the Self-Assembly of Suberin Hydrolysate, Betulin, and Their Hybrids

Muhammad Farooq, Charlotte Zborowski, Paula A. Nousiainen, Jenni Tienaho, Risto Korpinen, Monika Österberg 2025 Langmuir

Solventless Production of Thermoplastic Lignin Esters for Polymer Blends and Elastomers via Reactive Extrusion

Elijah Mark Garcia, Paula Nousiainen, Uula Hyväkkö, Monika Österberg 2025 ACS Sustainable Chemistry & Engineering

Ternary solid–liquid phase diagram prediction and batch cooling crystallization applications for mannitol in synthetic and fermentation systems

Mitra Ila, Paula Nousiainen, Donya Kamravamanesh, Tero Eerikäinen, Marjatta Louhi-Kultanen 2025 Chemical Engineering Journal

Application of kraft lignin as a colorant for screen printing on cotton

Janika Lehtonen, Pia Johansson, Sahar Babaeipour, Paula Nousiainen, Aravin Prince Periyasamy, Monika Österberg, Tapani Vuorinen 2025 Industrial Crops and Products

Upcycling Agricultural Waste for Functional Interfaces: Yellow Onion Skin-Derived Dyes for Cellulosic Materials

Ritesh Sharma, Peppi Toukola, Juha Jordan, Julia Vuorinen, Ngoc Huynh, Nikita Durandin, Mikko Herrala, Anja Primetta, Jaana Rysä, Monika Österberg, Paula Nousiainen, Päivi Laaksonen, Riikka Räisänen 2025 ACS Omega

Thin multifunctional coatings for textiles based on the layer-by-layer application of polyaromatic hybrid nanoparticles

Sahar Babaeipour, Paula Nousiainen, Erfan Kimiaei, Jenni Tienaho, Nadine Kohlhuber, Risto Korpinen, Kalle Kaipanen, Monika Österberg 2024 Materials Advances

Carbonisation of lignin in the presence of a eutectic salt mixture: Identifying the lignin properties that govern the characteristics of the resulting carbon material

Daria Robertson, Paula Nousiainen, Leena Pitkänen, Inge Schlapp-Hackl, Dmitrii Rusakov, Michael Hummel 2024 Journal of Analytical and Applied Pyrolysis

In Situ Adsorption of Red Onion (Allium cepa) Natural Dye on Cellulose Model Films and Fabrics Exploiting Chitosan as a Natural Mordant

Rafael Grande, Riikka Räisänen, Jinze Dou, Satu Rajala, Kiia Malinen, Paula A. Nousiainen, Monika Österberg 2023 ACS Omega

Transparent lignin nanoparticles for superhydrophilic antifogging coatings and photonic films

Karl Alexander Henn, Sahar Babaeipour, Susanna Forssell, Paula Nousiainen, Kristoffer Meinander, Pekka Oinas, Monika Österberg 2023 Chemical Engineering Journal

Interfacial catalysis and lignin nanoparticles for strong fire- and water-resistant composite adhesives

K. Alexander Henn, Susanna Forssell, Antti Pietiläinen, Nina Forsman, Ira Smal, Paula Nousiainen, Rahul Prasad Bangalore Ashok, Pekka Oinas, Monika Österberg 2022 Green Chemistry

Fractionation of Technical Lignin from Enzymatically Treated Steam-Exploded Poplar Using Ethanol and Formic Acid

Riku Maltari, Jussi Kontro, Klaus Koivu, Muhammad Farooq, Joona Mikkilä, Rui Zhang, Kristiina Hildén, Jussi Sipilä, Paula A. Nousiainen 2022 ACS Applied Polymer Materials

Production of Recombinant Laccase From Coprinopsis cinerea and Its Effect in Mediator Promoted Lignin Oxidation at Neutral pH

Jussi Kontro, Christina Lyra, Milla Koponen, Jaana Kuuskeri, Mika A. Kähkönen, Janne Wallenius, Xing Wan, Jussi Sipilä, Miia Mäkelä, Paula Nousiainen, Kristiina Hildén 2021 Frontiers in Bioengineering and Biotechnology

Vanillic acid and methoxyhydroquinone production from guaiacyl units and related aromatic compounds using Aspergillus niger cell factories

Ronnie J.M. Lubbers, Adiphol Dilokpimol, Paula A. Nousiainen, Răzvan C. Cioc, Jaap Visser, Pieter C.A. Bruijnincx, Ronald P. de Vries 2021 Microbial Cell Factories

Depolymerization of biorefinery lignin by improved laccases of the white-rot fungus Obba rivulosa

Janne Wallenius, Jussi Kontro, Christina Lyra, Jaana Kuuskeri, Xing Wan, Mika A. Kähkönen, Irshad Baig, Paul C.J. Kamer, Jussi Sipilä, Miia R. Mäkelä, Paula Nousiainen, Kristiina Hildén 2021 Microbial Biotechnology

Infrared and Raman spectra of lignin substructures

Peter Bock, Paula Nousiainen, Thomas Elder, Markus Blaukopf, Hassan Amer, Ronald Zirbs, Antje Potthast, Notburga Gierlinger 2020 Journal of Raman Spectroscopy

On the Effect of Hot-Water Pretreatment in Sulfur-Free Pulping of Aspen and Wheat Straw

Uula Hyväkkö, Riku Maltari, Tia Kakko, Jussi Kontro, Joona Mikkilä, Petri Kilpeläinen, Eric Enqvist, Panu Tikka, Kristiina Hildén, Paula Nousiainen, Jussi Sipilä 2020 ACS Omega

Applicability of Recombinant Laccases From the White-Rot Fungus Obba rivulosa for Mediator-Promoted Oxidation of Biorefinery Lignin at Low pH

Jussi Kontro, Riku Maltari, Joona Mikkilä, Mika Kähkönen, Miia R. Mäkelä, Kristiina Hildén, Paula Nousiainen, Jussi Sipilä 2020 Frontiers in Bioengineering and Biotechnology

Fungal Treatment Modifies Kraft Lignin for Lignin- And Cellulose-Based Carbon Fiber Precursors

Joona Mikkilä, Mikaela Trogen, Klaus A.Y. Koivu, Jussi Kontro, Jaana Kuuskeri, Riku Maltari, Zane Dekere, Marianna Kemell, Miia R. Mäkelä, Paula A. Nousiainen, Michael Hummel, Jussi Sipilä, Kristiina Hildén 2020 ACS Omega

Applicability of laccase mediator systems of recombinant laccase catalyzed oxidation of lignin at low pH

Jussi Heikki Samuli Kontro, Paula Annukka Nousiainen, Mika Antero Kähkönen, Uula T Hyväkkö, Joona Aleksi Mikkilä, Miia Riitta Mäkelä, Sari Kristiina Hilden, Antti Jussi Sipilä 2018

Exploring laccase mediator systems with acidic recombinant enzymes from Obba rivulosa

Jussi Heikki Samuli Kontro, Paula Annukka Nousiainen, Mika Antero Kähkönen, Joona Aleksi Mikkilä, Miia Riitta Mäkelä, Sari Kristiina Hilden, Antti Jussi Sipilä 2018

Biochemical characterization of laccases from the white-rot fungus Obba rivulosa

Mika Antero Kähkönen, Paula Annukka Nousiainen, Jussi Heikki Samuli Kontro, Mila Marinovic, Irshad Baig, Paul Kamer, Antti Jussi Sipilä, Miia Riitta Mäkelä, Sari Kristiina Hilden 2018

Selective Cleavage of Lignin β- O-4 Aryl Ether Bond by β-Etherase of the White-Rot Fungus Dichomitus squalens

Mila Marinović, Paula Nousiainen, Adiphol Dilokpimol, Jussi Kontro, Robin Moore, Jussi Sipilä, Ronald P. De Vries, Miia R. Mäkelä, Kristiina Hildén 2018 ACS Sustainable Chemistry & Engineering

Search for production of high-quality lignin from technical lignins by enzymatic catalysis

Joona Aleksi Mikkilä, Jaana Tuulia Kuuskeri, Miia Riitta Mäkelä, Zane Dekere, Jussi Heikki Samuli Kontro, Paula Annukka Nousiainen, Antti Jussi Sipilä, Sari Kristiina Hilden 2018

Two distinct enzymatic approaches for coupling fatty acids onto lignocellulosic materials

Katrin J. Greimel, Tukayi Kudanga, Paula Nousiainen, Jussi Sipilä, Enrique Herrero Acero, Gibson S. Nyanhongo, Georg M. Guebitz 2017 Process Biochemistry

Engineering towards catalytic use of fungal class-II peroxidases for dye-decolorizing and conversion of lignin model compounds

Taina Lundell, Elodie Bentley, Kristiina Hildén, Johanna Rytioja, Jaana Kuuskeri, Usenobong F. Ufot, Paula Nousiainen, Martin Hofrichter, Matti Wahlsten, Wendy Doyle, Andrew T. Smith 2017 Current Biotechnology

Effect of Fatty Acid Esterification on the Thermal Properties of Softwood Kraft Lignin

Klaus A.Y. Koivu, Hasan Sadeghifar, Paula A. Nousiainen, Dimitris S. Argyropoulos, Jussi Sipilä 2016 ACS Sustainable Chemistry & Engineering

Time-scale dynamics of proteome and transcriptome of the white-rot fungus Phlebia radiata

Jaana Kuuskeri, Mari Häkkinen, Pia Laine, Olli Pekka Smolander, Fitsum Tamene, Sini Miettinen, Paula Nousiainen, Marianna Kemell, Petri Auvinen, Taina Lundell 2016 Biotechnology for Biofuels

Aromatic metabolism of filamentous fungi in relation to the presence of aromatic compounds in plant biomass

Miia R. Mäkelä, Mila Marinović, Paula Nousiainen, April J.M. Liwanag, Isabelle Benoit, Jussi Sipilä, Annele Hatakka, Ronald P. de Vries, Kristiina S. Hildén 2015 Advances in Applied Microbiology

Phenolic mediators enhance the manganese peroxidase catalyzed oxidation of recalcitrant lignin model compounds and synthetic lignin

Paula Nousiainen, Jussi Kontro, Helmiina Manner, Annele Hatakka, Jussi Sipilä 2014 Fungal Genetics and Biology

Laser-induced fluorescence (LIF) of lignin and lignin model compounds in Raman spectroscopy

Anni Lahdetie, Paula Nousiainen, Jussi Sipilä, Tarja Tamminen, Anna-Stiina Jaaskelainen 2013 Holzforschung

Phenolic mediators boost manganese and versatile peroxidase catalyzed oxidation of lignocellulosic materials

Paula Annukka Nousiainen, Jussi Kontro, Helmiina Manner, Johanna Rytioja, Miia Mäkelä, Pekka Maijala, Taina Lundell, Annele Hatakka, Jussi Sipilä 2013

Origin of laser induced fluorescence of lignin

Anni Lähdetie, Paula Nousiainen, Jussi Sipilä, Anna-Stiina Jääskelainen 2012 243rd ACS National Meeting & Exposition, San Diego, CA, United States, March 25-29, 2012

Action of fungal laccases on lignin model compounds in organic solvents

Pekka Maijala, Maija-Liisa Mattinen, Paula Nousiainen, Jussi Kontro, Janne Asikkala, Jussi Sipilä, Liisa Viikari 2012 Journal of Molecular Catalysis B: Enzymatic

The wood rot ascomycete Xylaria polymorpha produces a novel GH78 glycoside hydrolase that exhibits α-L-rhamnosidase and feruloyl esterase activities and releases hydroxycinnamic acids from lignocelluloses

Do Huu Nghi, Britta Bittner, Harald Kellner, Nico Jehmlich, René Ullrich, Marek J. Pecyna, Paula Nousiainen, Jussi Sipilä, Le Mai Huong, Martin Hofrichter, Christiane Liers 2012 Applied and Environmental Microbiology

Lignin model compound studies to elucidate the effect of "natural" mediators on oxidoreductase-catalyzed degradation of lignocellulosic materials

P. Nousiainen, J. Kontro, Pekka Maijala, E. Uzan, A. Hatakka, A. Lomascolo, J. Sipilä 2012 Functional Materials from Renewable Sources

Phenolic mediators enhance the manganese peroxidase catalyzed oxidation of recalcitrant lignin model compounds

Paula Annukka Nousiainen, Jussi Heikki Samuli Kontro, Maija Helmiina Manner, Miia Riitta Mäkelä, Sari Kristiina Hilden, Pekka Mikael Maijala, Taina Kristina Lundell, Annele Inkeri Hatakka, Antti Jussi Sipilä 2012 OxiZymes 16.-19.9. 2012, proceedings book p. 123. Poster

The potential of phenolic mediators on manganese peroxidase catalyzed oxidation of lignocellulosic materials

Paula Annukka Nousiainen, Jussi Kontro, Helmiina Manner, Miia Mäkelä, Kristiina Hilden, Pekka Maijala, Taina Lundell, Annele Hatakka, Jussi Sipilä 2012 EWLP 2012

Laccase aided modification of nanofibrillated cellulose with dodecyl gallate

Päivi Saastamoinen, Maija-Liisa Mattinen, Ulla Hippi, Paula Nousiainen, Jussi Sipilä, Martina Lille, Anna Suurnäkki, Jaakko Pere 2012 BioResources

Oxidative cleavage of non-phenolic β-O-4 lignin model dimmers by an extracellular aromatic peroxygenase

Matthias Kinne, Marzena Poraj-Kobielska, René Ullrich, Paula Nousiainen, Jussi Sipilä, Katrin Scheibner, Kenneth E. Hammel, Martin Hofrichter 2011 Holzforschung

Oxidation of lignans and lignin model compounds by laccase in aqueous solvent systems

Maija-Liisa Mattinen, Pekka Maijala, Paula Nousiainen, Annika Smeds, Jussi Kontro, Jussi Sipilä, Tarja Tamminen, Stefan Willför, Liisa Viikari 2011 Journal of Molecular Catalysis B: Enzymatic

Oxidative polymerisation of models for phenolic lignin end-groups by laccase

Dimitri Areskogh, Jiebing Li, Paula Nousiainen, Göran Gellerstedt, Jussi Sipilä, Gunnar Henriksson 2010 Holzforschung

Sulfonation of phenolic end groups in lignin directs laccase-initiated reactions towards cross-linking

Dimitri Areskogh, Paula Nousiainen, Jiebing Li, Göran Gellerstedt, Jussi Sipilä, Gunnar Henriksson 2010 Industrial Biotechnology

Laccases from the white rot fungi Physisporinus rivulosus and Phlebia radiata: molecular characterization of thermotolerant oxidoreductases and reactions with mediator compounds

Kristiina Hilden, Taina Lundell, Miia Mäkelä, Johanna Rytioja, Paula Annukka Nousiainen, Jussi Sipilä, A Chernykh, L Golovleva, D Archer, Annele Hatakka 2010 1st Symposium on Biotechnology Applied to Lignocelluloses, Lignobiotech One

Molecular characterisation of thermotolerant laccases from the biopulping fungus Physisporinus rivulosus

Kristiina Hilden, Taina Lundell, Miia Mäkelä, Johanna Rytioja, Paula Annukka Nousiainen, Jussi Sipilä, D Archer, A Chernykh, L Golovleva, Annele Hatakka 2010 Oxidative enzymes as sustainable industrial biocatalysts (OESIB)

High redox potential laccases from the ligninolytic fungi Pycnoporus coccineus and Pycnoporus sanguineus suitable for white biotechnology: From gene cloning to enzyme characterization and applications

E. Uzan, P. Nousiainen, V. Balland, J. Sipilä, F. Piumi, D. Navarro, M. Asther, E. Record, A. Lomascolo 2010 Journal of Applied Microbiology

Analysis of ¹H and ¹³C{¹H} NMR spectral parameters of diphenylchloroarsine, diphenylcyanoarsine, and 10-chloro-5,10-dihydrophenarsazine: identification of the compounds through reference to simulated spectra

M. Mesilaakso, E.-L. Tolppa, P. Nousiainen 1997 Applied Spectroscopy

Modeling of the Kinetics of Alkali Fusion

Juha Lehtonen, Tapio Salmi, Antti Vuori, Heikki Haario, Paula Nousiainen 1995 Industrial and Engineering Chemistry Research

Honors and awards

Suomen väriyhdistyksen Iiris-palkinto BioColour-hankkeelle

Research groups

Publications