Department of Neuroscience and Biomedical Engineering

Molecular Nanoengineering

The Molecular Nanoengineering operates at the interface between nanoscience, molecular self-assembly, DNA nanotechnology and nanoplasmonics with particular focus on DNA-based artificial molecular systems with functionalities tailored for biosensing, nanoplasmonics and biomimetics.

Collaborations

Prof. Laura Na Liu, University of Heidelberg

Prof. Francesco Ricci, University of Rome

Prof. Masayuki Endo, Kyoto University

Prof. Ivan I. Smalyukh, University of Colorado at Boulder

Selected publications

A. Kuzyk, R. Jungmann, G. P. Acuna, N. Liu (2018): DNA Origami Route for Nanophotonics. ACS Photonics 5:1151–1163. https://pubs.acs.org/doi/10.1021/acsphotonics.7b01580
M. J. Urban, S. Both, C. Zhou, A. Kuzyk, K. Lindfors, T. Weiss, N. Liu (2018). Gold Nanocrystal-Mediated Sliding of Doublet DNA Origami Filaments. Nature Communications 9: 1454. https://www.nature.com/articles/s41467-018-03882-w
A. Kuzyk, M. J. Urban, A. Idili, F. Ricci, N. Liu (2017): Selective Control Of Reconfigurable Chiral Plasmonic Metamolecules. Science Advances 3:e1602803.
A. Kuzyk, Y. Yang, X. Duan, S. Stoll, A. O. Govorov, H. Sugiyama, M. Endo, N. Liu (2016): A Light-Driven Three-Dimensional Plasmonic Nanosystem that Translates Molecular Motion into Reversible Chiroptical Function. Nature Communications 7:10591.
A. Kuzyk, R. Schreiber, H. Zhang, A.O. Govorov, T. Liedl, N. Liu (2014): Reconfigurable 3D Plasmonic Metamolecules in the Visible Wavelength Range. Nature Materials 13:862.
M.B. Scheible, G. Pardatscher, A. Kuzyk, F.C. Simmel (2014): Single Molecule Characterization of DNA Binding and Strand Displacement Reactions on Lithographic DNA Origami Microarrays. Nano Letters 14:1627.
R. Schreiber, N. Luong, Z. Fan, A. Kuzyk, P.C. Nickels, T. Zhang, D.M. Smith, B. Yurke, W. Kuang, A. O. Govorov, T. Liedl (2013): Chiral Plasmonic DNA Nanostructures with Switchable Circular Dichroism. Nature Communications 4:2948.
G. Acuna, M. Bucher, I. H. Stein, C. Steinhauer, A. Kuzyk, P. Holzmeister, R. Schreiber, A. Moroz, F. D. Stefani, T. Liedl, F. C. Simmel, P. Tinnefeld (2012): Distance Dependence of Single-Fluorophore Quenching by Gold Nanoparticles Studied on DNA Origami. ACS Nano 6:3189.
A. Kuzyk, R. Schreiber, Z. Fan, G. Pardatscher, E.-M. Roller, A. Högele, F. C. Simmel, A. O. Govorov, T. Liedl (2012): DNA-based Self-Assembly of Chiral Plasmonic Nanostructures with Tailored Optical Response. Nature 483:311.
R. Jungmann, C. Steinhauer, M. Scheible, A. Kuzyk, P. Tinnefeld, F. C. Simmel (2010): Single-Molecule Kinetics and Super-Resolution Microscopy by Fluorescence Imaging of Transient Binding on DNA Origami. Nano Letters 10:4756.
T. K. Hakala, J. J. Toppari, A. Kuzyk, M. Pettersson, H. Tikkanen, H. Kunttu, P. Törmä (2009): Vacuum Rabi Splitting and Strong Coupling Dynamics for Surface Plasmon Polaritons and Rhodamine 6G Molecules. Physical Review Letters 103:053602.
A. Kuzyk, K. T. Laitinen, P. Törmä (2009): DNA Origami as a Nanoscale Template for Protein Assembly. Nanotechnology 20:235305.
A. Kuzyk, B. Yurke, J. J. Toppari, V. Linko, P. Törmä (2008): Dielectrophoretic Trapping of DNA Origami. Small 4:447.