Department of Neuroscience and Biomedical Engineering

Molecular Nanoengineering

The Molecular Nanoengineering operates at the interface between nanoscience, molecular self-assembly, DNA nanotechnology and nanoplasmonics with particular focus on DNA-based artificial molecular systems with functionalities tailored for biosensing, nanoplasmonics and biomimetics.

Members

Dr. Svitlana Filonenko, postdoc (now: group manager at MPI of Colloids and Interfaces)
Ilona Leppänen, MSc (now: research scientist at VTT)
Nguyen Hoang Vu, MSc

P. Zhan, M. J. Urban, S. Both, X. Duan, A. Kuzyk, T. Weiss, N. Liu (2019): DNA-assembled Nanoarchitectures with Multiple Components in Regulated and Coordinated Motion. Science Advances 5: eaax6023.
M-K Nguyen, A. Kuzyk (2019): Reconfigurable Chiral Plasmonics beyond Single Chiral Centers. ACS Nano 13:13615.
Q. Liu, A. Kuzyk, M. Endo, I. Smalyukh (2019): Plasmonic DNA-Origami with Photo-Switchable Chirality in Liquid Crystals. Optics Letters 44:2831.
T. Funck, F. Nicoli, A. Kuzyk, T. Liedl (2018): Sensing Picomolar Concentrations of RNA using Switchable Plasmonic Chirality. Angewandte Chemie International Edition 57:13495.
Y. Huang, M-K Nguyen, A. K. Natarajan, V. H. Nguyen, A. Kuzyk (2018): DNA Origami-Based Chiral Plasmonic Sensing Device. ACS Applied Materials & Interfaces 10:44221.
A. Kuzyk, R. Jungmann, G. P. Acuna, N. Liu (2018): DNA Origami Route for Nanophotonics. ACS Photonics 5:1151–1163.
M. J. Urban, S. Both, C. Zhou, A. Kuzyk, K. Lindfors, T. Weiss, N. Liu (2018). Gold Nanocrystal-Mediated Sliding of Doublet DNA Origami Filaments. Nature Communications 9: 1454.
A. Kuzyk, M. J. Urban, A. Idili, F. Ricci, N. Liu (2017): Selective Control Of Reconfigurable Chiral Plasmonic Metamolecules. Science Advances 3:e1602803.
A. Kuzyk, Y. Yang, X. Duan, S. Stoll, A. O. Govorov, H. Sugiyama, M. Endo, N. Liu (2016): A Light-Driven Three-Dimensional Plasmonic Nanosystem that Translates Molecular Motion into Reversible Chiroptical Function. Nature Communications 7:10591.
A. Kuzyk, R. Schreiber, H. Zhang, A.O. Govorov, T. Liedl, N. Liu (2014): Reconfigurable 3D Plasmonic Metamolecules in the Visible Wavelength Range. Nature Materials 13:862.
M.B. Scheible, G. Pardatscher, A. Kuzyk, F.C. Simmel (2014): Single Molecule Characterization of DNA Binding and Strand Displacement Reactions on Lithographic DNA Origami Microarrays. Nano Letters 14:1627.
R. Schreiber, N. Luong, Z. Fan, A. Kuzyk, P.C. Nickels, T. Zhang, D.M. Smith, B. Yurke, W. Kuang, A. O. Govorov, T. Liedl (2013): Chiral Plasmonic DNA Nanostructures with Switchable Circular Dichroism. Nature Communications 4:2948.
G. Acuna, M. Bucher, I. H. Stein, C. Steinhauer, A. Kuzyk, P. Holzmeister, R. Schreiber, A. Moroz, F. D. Stefani, T. Liedl, F. C. Simmel, P. Tinnefeld (2012): Distance Dependence of Single-Fluorophore Quenching by Gold Nanoparticles Studied on DNA Origami. ACS Nano 6:3189.
A. Kuzyk, R. Schreiber, Z. Fan, G. Pardatscher, E.-M. Roller, A. Högele, F. C. Simmel, A. O. Govorov, T. Liedl (2012): DNA-based Self-Assembly of Chiral Plasmonic Nanostructures with Tailored Optical Response. Nature 483:311.
R. Jungmann, C. Steinhauer, M. Scheible, A. Kuzyk, P. Tinnefeld, F. C. Simmel (2010): Single-Molecule Kinetics and Super-Resolution Microscopy by Fluorescence Imaging of Transient Binding on DNA Origami. Nano Letters 10:4756.