Making colours out of gold and DNA
Gold nanoparticles are arranged by custom DNA molecules to produce colours
Molecular Nanoengineering
The Molecular Nanoengineering group operates at the interface between nanoscience, molecular self-assembly, DNA nanotechnology and nanoplasmonics with particular focus on DNA-based artificial molecular systems with functionalities tailored for biosensing, nanophotonics and biomimetics.
Members
Mohammed Mustafa A Al Hussain
Doctoral Researcher
T314 Dept. Neuroscience and Biomedical Engineering
Anni Lindfors
Research Assistant
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Dr. Svitlana Filonenko, postdoc (now: group manager at MPI of Colloids and Interfaces)
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Susanna Hällsten, MSc
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Arttu Lehtonen, MSc (now: doctoral candidate in Juho Pokki lab)
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Ilona Leppänen, MSc (now: research scientist at VTT)
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Dr. Sesha Manuguri (current position: optical engineer, Microsoft, Helsinki)
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Kalle Mikkola, MSc
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Ashwin Natarajan (current position: postdoc, Daumke Lab, Max-Delbrück-Center for Molecular Medicine, Berlin)
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Dr. Minh-Kha Nguyen (now: Ho Chi Minh City University of Technology (HCMUT), Vietnam)
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Joonas Ryssy (current position: postdoc, Schaufelberger Group, Department of Chemistry, KTH Royal Institute of Technology, Stockholm)
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Nguyen Hoang Vu, MSc (now: DNAnexus, Vietnam)
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J. Ryssy, A. K. Natarajan, J. Wang, A. J. Lehtonen, M.‐K. Nguyen, R. Klajn, A. Kuzyk (2021): Light‐Responsive Dynamic DNA‐Origami‐Based Plasmonic Assemblies. Angewandte Chemie International Edition 60: 5859.
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M.-K. Nguyen, V. H. Nguyen, A. K. Natarajan, Y. Huang, J. Ryssy, B. Shen, A. Kuzyk (2020): Ultrathin Silica Coating of DNA Origami Nanostructures. Chemistry of Materials 32: 6657.
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P. Zhan, M. J. Urban, S. Both, X. Duan, A. Kuzyk, T. Weiss, N. Liu (2019): DNA-assembled Nanoarchitectures with Multiple Components in Regulated and Coordinated Motion. Science Advances 5: eaax6023.
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M-K Nguyen, A. Kuzyk (2019): Reconfigurable Chiral Plasmonics beyond Single Chiral Centers. ACS Nano 13:13615.
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Q. Liu, A. Kuzyk, M. Endo, I. Smalyukh (2019): Plasmonic DNA-Origami with Photo-Switchable Chirality in Liquid Crystals. Optics Letters 44:2831.
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T. Funck, F. Nicoli, A. Kuzyk, T. Liedl (2018): Sensing Picomolar Concentrations of RNA using Switchable Plasmonic Chirality. Angewandte Chemie International Edition 57:13495.
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Y. Huang, M-K Nguyen, A. K. Natarajan, V. H. Nguyen, A. Kuzyk (2018): DNA Origami-Based Chiral Plasmonic Sensing Device. ACS Applied Materials & Interfaces 10:44221.
- A. Kuzyk, R. Jungmann, G. P. Acuna, N. Liu (2018): DNA Origami Route for Nanophotonics. ACS Photonics 5:1151–1163.
- M. J. Urban, S. Both, C. Zhou, A. Kuzyk, K. Lindfors, T. Weiss, N. Liu (2018). Gold Nanocrystal-Mediated Sliding of Doublet DNA Origami Filaments. Nature Communications 9: 1454.
- A. Kuzyk, M. J. Urban, A. Idili, F. Ricci, N. Liu (2017): Selective Control Of Reconfigurable Chiral Plasmonic Metamolecules. Science Advances 3:e1602803.
- A. Kuzyk, Y. Yang, X. Duan, S. Stoll, A. O. Govorov, H. Sugiyama, M. Endo, N. Liu (2016): A Light-Driven Three-Dimensional Plasmonic Nanosystem that Translates Molecular Motion into Reversible Chiroptical Function. Nature Communications 7:10591.
- A. Kuzyk, R. Schreiber, H. Zhang, A.O. Govorov, T. Liedl, N. Liu (2014): Reconfigurable 3D Plasmonic Metamolecules in the Visible Wavelength Range. Nature Materials 13:862.
- M.B. Scheible, G. Pardatscher, A. Kuzyk, F.C. Simmel (2014): Single Molecule Characterization of DNA Binding and Strand Displacement Reactions on Lithographic DNA Origami Microarrays. Nano Letters 14:1627.
- R. Schreiber, N. Luong, Z. Fan, A. Kuzyk, P.C. Nickels, T. Zhang, D.M. Smith, B. Yurke, W. Kuang, A. O. Govorov, T. Liedl (2013): Chiral Plasmonic DNA Nanostructures with Switchable Circular Dichroism. Nature Communications 4:2948.
- A. Kuzyk, R. Schreiber, Z. Fan, G. Pardatscher, E.-M. Roller, A. Högele, F. C. Simmel, A. O. Govorov, T. Liedl (2012): DNA-based Self-Assembly of Chiral Plasmonic Nanostructures with Tailored Optical Response. Nature 483:311.
Collaborations
- Prof. Laura Na Liu, University of Heidelberg
- Prof. Rafal Klajn, Weizmann Institute of Science
- Prof. Guillermo P. Acuna, University of Fribourg
Recent
Research project develops electrically controlled artificial molecular machines
Electronically controlled molecular machines would be faster as well as easier to manufacture, as they would not need to rely on sophisticated chemical synthesis.
Tiny origami controlled by light
Nanosized hinges can fold and unfold on command
Nantech brought nearly one hundred international researchers to Espoo
Understanding of computer science and mathematics becomes increasingly important in the field of DNA nanotechnology, says Professor Pekka Orponen
Self-assembled nanostructures can be selectively controlled
DNA self-assembly allows the unprecedented control of the optical properties of plasmonic metamolecules.
DNA builder gets inspiration from nature
Being able to build things in nanoscale can lead to useful bioinspired applications, says Assistant Professor Anton Kuzyk.
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