News

Sometimes just watching hurts—and the signs of pain are seen in the brain

Brain research helps to develop diagnostics and new therapies for people suffering from complex regional pain syndrome CRPS.

 

Patients suffering from CRPS may feel pain and show abnormal brain activations while watching a hand actions. Credit: Jaakko Hotta, Aalto University.

Some people claim to experience pain just watching something painful to happen. This is true especially of people suffering from complex regional pain syndrome (CRPS), a disabling chronic pain disorder in a limb. In CPRS patients, both own movements and just observing other persons’ movements may aggravate the pain.

When you hurt yourself, pain receptors in the body send signals to different parts of the brain. As the result, you experience pain. Researchers in Aalto University, Finland, found that when CRPS patients feel pain caused by observing other person’s movements, their brains display abnormal activation in many such areas that respond to normal physical pain. Thus the pain that the CRPS patients felt during movement observation presented similarities to the “normal” pain associated with tissue damage.

- CPRS is a very complex disease with devastating chronic pain. Its pathophysiology is incompletely understood and definitive biomarkers are lacking. Our discovery may help to develop diagnostics and therapeutic strategies for CRPS patients, tells neurologist Jaakko Hotta, Doctoral Candidate at Aalto University.

In the study, the researchers analyzed functional magnetic resonance images from 13 upper-limb CRPS patients and 13 healthy control subjects who were viewing brief videos of hand actions, such as a hand squeezing a ball with maximum force.

In the CPRS patients, watching hand actions was associated with abnormal brain activation patterns and a pattern-classification analysis differentiated the patients from the healthy subjects. These findings indicate that CRPS affects brain areas related to both pain processing and motor control.

The study was published on the Journal of Pain, the official journal of the American Pain Society.

For more information:
Jaakko Hotta, Doctoral Candidate / Neurologist
Aalto University, School of Science
[email protected]
Tel: +358 50 57 12640

Research article: Jaakko Hotta, Jukka Saari, Miika Koskinen, Yevhen Hlushchuk, Nina Forss, Riitta Hari: Abnormal brain responses to action observation in complex regional pain syndrome. Journal of Pain 2016. DOI: http://dx.doi.org/10.1016/j.jpain.2016.10.017

  • Published:
  • Updated:
Share
URL copied!

Related news

Taiteellinen kuva panssaroidusta superhydrofobisesta pinnasta, joka kestää iskuja ja hylkii nesteitä tehokkaasti. Kuva: Juha Juvonen.
Cooperation, Press releases, Research & Art Published:

New funding to commercialise high-tech liquid-repelling coatings

New funding to get damage-resistant, liquid-repelling surfaces out of the laboratory and onto solar panels, skis, and more
The computer game could help in the treatment of depression alongside therapy and drug treatment. Picture: Matias Palva’s research group, Aalto University.
Press releases Published:

Researchers developing computer game to treat depression

Playing a therapeutic action game can ease symptoms in patients with depression, and improve their cognitive performance
An electron microscope image of the device used to extract entangled electrons
Press releases Published:

Entangling electrons with heat

Entanglement is key for quantum computing and communications technology; Aalto researchers can now extract entangled electrons using heat
Ihminen tekemässä työtä laboratotiossa.
Press releases, Research & Art Published:

How to motivate people to comply voluntarily with necessary restrictions – 13 principles for effective COVID-19 related communication

Decision-makers and experts should support people's autonomy, competence and relatedness in their COVID-19 related communications with citizens.