ABC Seminar: High frequency oscillations as biomarkers for epilepsy surgery in intracranial EEG, but not only!

Welcome to the ABC Seminar! This seminar series is open for everyone and you don't need to register. The talk will take place in the Auditorium F239a in Health Technology House (Otakaari 3). After the talk, coffee and pulla will be served.

Speaker: Dr. Tommaso Fedele, Institute of Cognitive Neuroscience, HSE, Moscow, Russia Federation

Title: High frequency oscillations as biomarkers for epilepsy surgery in intracranial EEG, but not only!

Abstract: Neurophysiological assessment in epilepsy patients currently suffers of reliable biomarkers for the identification of the epileptogenic zone to support optimal surgical intervention. High frequency oscillations (HFOs) are recognized as biomarkers for epileptogenic brain tissue. A remaining challenge for epilepsy surgery is the prospective classification of tissue sampled by individual electrode contacts. In this presentation I describe the automated detection of HFO in intracranial EEG recordings and the predictive value of HFO with respect to seizure outcome. Finally, I discuss the challenge and the potential of HFO detection in non- invasive recordings.

Bio: Dr. Tommaso Fedele received his PhD from TU Berlin, Germany, where he studied high frequency oscillations in low noise EEG: from spike-like activity to non invasive recodings. After a post-doc at the University Hospital of Zurich, Switzerland, where he worked on invasive EEG recordings in epilepsy patients, he has now joined the MEG group at the Institute of Cognitive Neuroscience of the Higher School of Economics in Moscow, Russia. His main interest is the development of neurophysiological biomarkers for epilepsy surgery.