Markus Linder

T107 Bioproducts and Biosystems


I work on making different microbes do useful things. Microbes are incredibly versatile systems for producing different types of materials and chemicals. The microbes can produce proteins that we build materials from. These materials can be something like silk, or cellulose. The special thing is that we can use genetic engineering to program so that the microbes make the materials or chemicals that we want. We also study how microbes communicate with each other in order to get them working better together to make the things we want them to do. When the microbes have made components or chemicals to make materials form our real challenge is to actually construct the materials. This involves using different assembly techniques and characterization. In the future I think that this way of using engineered microbes to produce materials and chemical will allow a sustainable green technology.

Also look at: The HYBER Centre.

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Honors and awards

VTT Prize for Scientific Excellence

Award or honor granted for a specific work Department of Bioproducts and Biosystems Jan 1998

Leading edge-lecturer

Award or honor granted for academic or artistic career Department of Bioproducts and Biosystems Jan 2015

Research groups

  • Biomolecular Materials, Professor


Exploration of Chemical Diversity in Intercellular Quorum Sensing Signalling Systems in Prokaryotes

Christopher Jonkergouw, Pihla Savola, Ekaterina Osmekhina, Joeri van Strien, Piotr Batys, Markus B. Linder 2024 Angewandte Chemie - International Edition

Microwave hydrolysis, as a sustainable approach in the processing of seaweed for protein and nanocellulose management

Anna Trubetskaya, Huy Quang Lê, Jenni Leppiniemi, Tetyana Koso, Teemu Välisalmi, Markus B. Linder, Italo Pisano, Jinze Dou, J. J. Leahy, Eero Kontturi 2024 Algal Research

Molecular Engineering of a Spider Silk and Mussel Foot Hybrid Protein Gives a Strong and Tough Biomimetic Adhesive

Yin Yin, Nelmary Roas-Escalona, Markus B. Linder 2024 Advanced Materials Interfaces

Rapid Improvement of Fiber Tensile Properties via in situ Biomimetic Robotic Pulling and Bayesian Optimization

Houari Bettahar, David Blanco Mulero, Ville Kyrki, Markus Linder, Quan Zhou 2023 Advanced Intelligent Systems

Biomolecular Click Reactions Using a Minimal pH-Activated Catcher/Tag Pair for Producing Native-Sized Spider-Silk Proteins

Ruxia Fan, Johanna Hakanpää, Karoliina Elfving, Helena Taberman, Markus B. Linder, A. Sesilja Aranko 2023 Angewandte Chemie - International Edition

Triblock Proteins with Weakly Dimerizing Terminal Blocks and an Intrinsically Disordered Region for Rational Design of Condensate Properties

Dmitrii Fedorov, Nelmary Roas-Escalona, Dmitry Tolmachev, Adam L. Harmat, Alberto Scacchi, Maria Sammalkorpi, A. Sesilja Aranko, Markus B. Linder 2023 Small

A Minispidroin Guides the Molecular Design for Cellular Condensation Mechanisms in S. cerevisiae

Jianhui Feng, Bartosz Gabryelczyk, Isabell Tunn, Ekaterina Osmekhina, Markus Linder 2023 ACS Synthetic Biology

Shaping Liquid Droplets on an Active Air–Ferrofluid Interface

P. A. Diluka Harischandra, Teemu Välisalmi, Zoran Cenev, Markus Linder, Quan Zhou 2023 Langmuir

Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii

Christopher Jonkergouw, Ngong Kodiah Beyeh, Ekaterina Osmekhina, Katarzyna Leskinen, S. Maryamdokht Taimoory, Dmitrii Fedorov, Eduardo Anaya-Plaza, Mauri A. Kostiainen, John F. Trant, Robin H.A. Ras, Päivi Saavalainen, Markus B. Linder 2023 Nature Communications

pH dependence of the assembly mechanism and properties of poly(l-lysine) and poly(l-glutamic acid) complexes

Tuuva Kastinen, Dawid Lupa, Piotr Bonarek, Dmitrii Fedorov, Maria Morga, Markus B. Linder, Jodie L. Lutkenhaus, Piotr Batys, Maria Sammalkorpi 2023 Physical Chemistry Chemical Physics