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Cellular Biophysics

Our main interest is in the molecular mechanisms of photoreceptor signaling and increasingly in the mechanisms of neurodegeneration in certain retinal diseases.
Aalto-yliopisto, liput / kuvaaja: Aino Huovio

Our research involves the use of genetically modified mice and the use and development of state-of-the-art electrophysiological recording techniques and approaches, from single-cell recording to electroretinography (ERG) across the isolated retina and in vivo ERG.

Presently our research is focused on two main areas:

  1. We study the molecular mechanisms controlling the gain and kinetics of photoreceptor signaling in various light conditions, especially the calcium-controlled feedback
  2. We aim at developing novel therapies for age-related macular degeneration (AMD).