Jarno Mäkelä

Jarno Mäkelä

Assistant Professor
Assistant Professor
T314 Dept. Neuroscience and Biomedical Engineering

The Single-Molecule Dynamics in Cells group takes an interdisciplinary approach to solve fundamental questions about how living systems adapt to extreme environments, employing a range of techniques from biophysics, molecular biology, genetics, to computational biology. The research will also contribute to the development of robust synthetic biology applications and novel assay solutions.

Keywords: Biophysics, Single-molecule imaging, Machine learning, Cell biology, Microbiology, Temperature adaptation, Extremophiles.

Group website: https://www.aalto.fi/en/department-of-neuroscience-and-biomedical-engineering/single-molecule-dynamics-in-cells

Full researcher profile
https://research.aalto.fi/...
Telefonnummer
+358503470990

Publikationer

Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

Jarno Mäkelä, Alexandros Papagiannakis, Wei-Hsiang Lin, Michael C. Lanz, Skye Glenn, Matthew Swaffer, Georgi K. Marinov, Jan M. Skotheim, Christine Jacobs-Wagner 2024

Dynamics of bacterial operons during genome-wide stresses

Rahul Jagadeesan, Suchintak Dash, Cristina S.D. Palma, Ines S.C. Baptista, Vatsala Chauhan, Jarno Mäkelä, Andre S. Ribeiro 2023

Competitive binding of MatP and topoisomerase IV to the MukB hinge domain

Gemma L.M. Fisher, Jani R. Bolla, Karthik V. Rajasekar, Jarno Mäkelä, Rachel Baker, Man Zhou, Josh P. Prince, Mathew Stracy, Carol V. Robinson, Lidia K. Arciszewska, David J. Sherratt 2021 eLife

Nonrandom segregation of sister chromosomes by Escherichia coli MukBEF

Jarno Mäkelä, Stephan Uphoff, David J. Sherratt 2021 Proceedings of the National Academy of Sciences of the United States of America

Acyl carrier protein promotes MukBEF action in Escherichia coli chromosome organization-segregation

Josh P. Prince, Jani R. Bolla, Gemma L.M. Fisher, Jarno Mäkelä, Marjorie Fournier, Carol V. Robinson, Lidia K. Arciszewska, David J. Sherratt 2021 Nature Communications

Catching an invader

Jarno Mäkelä, David J. Sherratt 2020 Nature Reviews Microbiology

Organization of the Escherichia coli Chromosome by a MukBEF Axial Core

Jarno Mäkelä, David J. Sherratt 2020 Molecular Cell

SMC complexes organize the bacterial chromosome by lengthwise compaction

Jarno Mäkelä, David Sherratt 2020 Current Genetics

Choosing the right label for single-molecule tracking in live bacteria

Nehir Banaz, Jarno Mäkelä, Stephan Uphoff 2019 Journal of Physics D: Applied Physics

Self-organised segregation of bacterial chromosomal origins

Andreas Hofmann, Jarno Mäkelä, David J. Sherratt, Dieter Heermann, Seán M. Murray 2019 eLife