Bioprocess Engineering

Bioprocess engineering group led by Prof. Sandip Bankar is dedicated to develop sustainable, efficient yet economic bioprocesses for industrially valuable biomolecules. We work in the areas of fermentation and purification of biomolecules, protein engineering for enhanced yields and metabolic engineering. Currently, we are also working to synthesise bio-based materials from sustainable biomass. The laboratory has been actively working on conversion of lignocellulosic biomass into biochemicals, with special emphasis on improved bioprocesses for biofuels, proteins and therapeutic molecules.
Bioprocess Engineering Group

Research themes

Production and downstream processing of biomolecules

Bioprocess engineering lab emphasizes on fermentative production, metabolic engineering and downstream processing of biochemicals such as liquid biofuels, acids, enzymes, and biopolymers as well as therapeutic proteins, high fiber products and rare sugars. We are also striving to utilise in-situ bacterial cellulose modifications for its high end applications in functional materials area. 

Process development by using statistical tools, general kinetic reactions and metabolic engineering

We are working to tackle the difficulties associated with mass transfer of gaseous substrates in liquid media in bioprocesses. Our efforts also include design of continuous multistage bioreactors coupled with in situ product recovery.

Modeling and simulation for scale up studies

Laboratory research also encompasses modeling and control of continuous high-temperature short-time food processing, producing high fiber products utilizing brewer’s spent grain, fuzzy logic and neural network modeling, expert system building for food process, pilot scale enzyme crystallization, biotechnical production of rare sugar such as L-fucose and fucose polymer.

Latest publications

Biohybrid materials, Department of Bioproducts and Biosystems, Bioprocess engineering

Stabilization of cutinase by covalent attachment on magnetic nanoparticles and improvement of its catalytic activity by ultrasonication

Publishing year: 2019 ULTRASONICS SONOCHEMISTRY
Department of Chemical and Metallurgical Engineering, Bioprocess engineering, Department of Bioproducts and Biosystems

Strategic intensification in butanol production by exogenous amino acid supplementation

Publishing year: 2019 Bioresource Technology
Department of Bioproducts and Biosystems, Bioprocess engineering

Mixing efficiency studies in an airlift bioreactor with helical flow promoters for improved reactor performance

Publishing year: 2019 Chemical Engineering and Processing - Process Intensification
Department of Bioproducts and Biosystems, Bioprocess engineering

Improvements in the extraction of bioactive compounds by enzymes

Publishing year: 2019 Current Opinion in Food Science
Bioprocess engineering, Department of Bioproducts and Biosystems

Novel multistage solid–liquid circulating fluidized bed

Publishing year: 2019 Particulate Science and Technology
Department of Chemical and Metallurgical Engineering, Department of Bioproducts and Biosystems, Bioprocess engineering

Solid-liquid circulating fluidized bed

Publishing year: 2019 REVIEWS IN CHEMICAL ENGINEERING
Department of Bioproducts and Biosystems, Bioprocess engineering

Process intensification strategies for enhanced holocellulose solubilization

Publishing year: 2018 Journal of Cleaner Production
Bioorganic Chemistry, Department of Chemistry and Materials Science, Bioprocess engineering, Department of Bioproducts and Biosystems, Department of Biotechnology and Chemical Technology

Fermentative production of extracellular amylase from novel amylase producer, Tuber maculatum mycelium, and its characterization

Publishing year: 2018 Preparative Biochemistry and Biotechnology
Department of Bioproducts and Biosystems, Bioprocess engineering

Novel multistage solid-liquid circulating fluidized bed

Publishing year: 2018 Particuology
Department of Bioproducts and Biosystems, Bioprocess engineering

Role of trace elements as cofactor

Publishing year: 2018 ACS Sustainable Chemistry and Engineering
More information on our research in the Research database.
Research database

Research group members

Tero Eerikäinen

Tero Eerikäinen

Department of Bioproducts and Biosystems
University Teacher
Sandip Bankar

Sandip Bankar

Department of Bioproducts and Biosystems
Assistant Professor
He Li

He Li

Department of Bioproducts and Biosystems
Postdoctoral Researcher

Riikka Särkelä

Department of Bioproducts and Biosystems
Doctoral Candidate

Vijaya Chandgude

Department of Bioproducts and Biosystems
Doctoral Candidate
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